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Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives

Post-translational methylation of histone lysine or arginine residues plays important roles in gene regulation and other physiological processes. Aberrant histone methylation caused by a gene mutation, translocation, or overexpression can often lead to initiation of a disease such as cancer. Small m...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Song, Yongcheng, Wu, Fangrui, Wu, Jingyu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912745/
https://ncbi.nlm.nih.gov/pubmed/27316347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0279-9
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