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Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives
Post-translational methylation of histone lysine or arginine residues plays important roles in gene regulation and other physiological processes. Aberrant histone methylation caused by a gene mutation, translocation, or overexpression can often lead to initiation of a disease such as cancer. Small m...
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| 出版年: | J Hematol Oncol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4912745/ https://ncbi.nlm.nih.gov/pubmed/27316347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0279-9 |
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