A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity

Stem cell identity depends on the integration of extrinsic and intrinsic signals, which directly influence the maintenance of their epigenetic state. Although Myc transcription factors play a major role in stem cell self-renewal and pluripotency, their integration with signalling pathways and epigen...

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Опубликовано в: :Nat Commun
Главные авторы: Fagnocchi, Luca, Cherubini, Alessandro, Hatsuda, Hiroshi, Fasciani, Alessandra, Mazzoleni, Stefania, Poli, Vittoria, Berno, Valeria, Rossi, Riccardo L., Reinbold, Rolland, Endele, Max, Schroeder, Timm, Rocchigiani, Marina, Szkarłat, Żaneta, Oliviero, Salvatore, Dalton, Stephen, Zippo, Alessio
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912626/
https://ncbi.nlm.nih.gov/pubmed/27301576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11903
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