A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity

Stem cell identity depends on the integration of extrinsic and intrinsic signals, which directly influence the maintenance of their epigenetic state. Although Myc transcription factors play a major role in stem cell self-renewal and pluripotency, their integration with signalling pathways and epigen...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Fagnocchi, Luca, Cherubini, Alessandro, Hatsuda, Hiroshi, Fasciani, Alessandra, Mazzoleni, Stefania, Poli, Vittoria, Berno, Valeria, Rossi, Riccardo L., Reinbold, Rolland, Endele, Max, Schroeder, Timm, Rocchigiani, Marina, Szkarłat, Żaneta, Oliviero, Salvatore, Dalton, Stephen, Zippo, Alessio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912626/
https://ncbi.nlm.nih.gov/pubmed/27301576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11903
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