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Myc Regulates the Transcription of the PRC2 Gene To Control the Expression of Developmental Genes in Embryonic Stem Cells

Myc family members are critical to maintain embryonic stem cells (ESC) in the undifferentiated state. However, the mechanism by which they perform this task has not yet been elucidated. Here we show that Myc directly upregulates the transcription of all core components of the Polycomb repressive com...

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書誌詳細
主要な著者: Neri, Francesco, Zippo, Alessio, Krepelova, Anna, Cherubini, Alessandro, Rocchigiani, Marina, Oliviero, Salvatore
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2012
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272981/
https://ncbi.nlm.nih.gov/pubmed/22184065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06148-11
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