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Myc Regulates the Transcription of the PRC2 Gene To Control the Expression of Developmental Genes in Embryonic Stem Cells

Myc family members are critical to maintain embryonic stem cells (ESC) in the undifferentiated state. However, the mechanism by which they perform this task has not yet been elucidated. Here we show that Myc directly upregulates the transcription of all core components of the Polycomb repressive com...

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Hlavní autoři: Neri, Francesco, Zippo, Alessio, Krepelova, Anna, Cherubini, Alessandro, Rocchigiani, Marina, Oliviero, Salvatore
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272981/
https://ncbi.nlm.nih.gov/pubmed/22184065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06148-11
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