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Myc Regulates the Transcription of the PRC2 Gene To Control the Expression of Developmental Genes in Embryonic Stem Cells

Myc family members are critical to maintain embryonic stem cells (ESC) in the undifferentiated state. However, the mechanism by which they perform this task has not yet been elucidated. Here we show that Myc directly upregulates the transcription of all core components of the Polycomb repressive com...

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Detalhes bibliográficos
Main Authors: Neri, Francesco, Zippo, Alessio, Krepelova, Anna, Cherubini, Alessandro, Rocchigiani, Marina, Oliviero, Salvatore
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272981/
https://ncbi.nlm.nih.gov/pubmed/22184065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06148-11
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