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Neuropathological assessment and validation of mouse models for Alzheimer's disease: applying NIA-AA guidelines

Dozens of transgenic mouse models, generally based on mutations associated with familial Alzheimer's disease (AD), have been developed, in part, for preclinical testing of candidate AD therapies. However, none of these models has successfully predicted the clinical efficacy of drugs for treatin...

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Xehetasun bibliografikoak
Argitaratua izan da:Pathobiol Aging Age Relat Dis
Egile Nagusiak: Keene, C. Dirk, Darvas, Martin, Kraemer, Brian, Liggitt, Denny, Sigurdson, Christina, Ladiges, Warren
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Co-Action Publishing 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912600/
https://ncbi.nlm.nih.gov/pubmed/27317189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3402/pba.v6.32397
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