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Neuropathological assessment and validation of mouse models for Alzheimer's disease: applying NIA-AA guidelines
Dozens of transgenic mouse models, generally based on mutations associated with familial Alzheimer's disease (AD), have been developed, in part, for preclinical testing of candidate AD therapies. However, none of these models has successfully predicted the clinical efficacy of drugs for treatin...
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| Опубликовано в: : | Pathobiol Aging Age Relat Dis |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Co-Action Publishing
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4912600/ https://ncbi.nlm.nih.gov/pubmed/27317189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3402/pba.v6.32397 |
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