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Neuropathological assessment and validation of mouse models for Alzheimer's disease: applying NIA-AA guidelines
Dozens of transgenic mouse models, generally based on mutations associated with familial Alzheimer's disease (AD), have been developed, in part, for preclinical testing of candidate AD therapies. However, none of these models has successfully predicted the clinical efficacy of drugs for treatin...
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| Publicado no: | Pathobiol Aging Age Relat Dis |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Co-Action Publishing
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4912600/ https://ncbi.nlm.nih.gov/pubmed/27317189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3402/pba.v6.32397 |
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