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PERK integrates oncogenic signaling and cell survival during cancer development
Unfolded protein responses (UPR), consisting of three major transducers PERK, IRE1 and ATF6, occur in the midst of a variety of intracellular and extracellular challenges that perturb protein folding in the endoplasmic reticulum (ER). ER stress occurs and is thought to be a contributing factor to a...
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| Pubblicato in: | J Cell Physiol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4912452/ https://ncbi.nlm.nih.gov/pubmed/26864318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25336 |
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