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Kinase-Dependent and Independent Roles for PTK6 in Colon Cancer

Disruption of the gene encoding Protein Tyrosine Kinase 6 (Ptk6) delayed differentiation and increased growth in the mouse intestine. However, Ptk6 null mice were also resistant to azoxymethane-induced colon tumorigenesis. To further explore functions of PTK6 in colon cancer, expression of epithelia...

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Bibliografische gegevens
Gepubliceerd in:Mol Cancer Res
Hoofdauteurs: Mathur, Priya S., Gierut, Jessica J., Guzman, Grace, Xie, Hui, Xicola, Rosa M., Llor, Xavier, Chastkofsky, Michael I., Perekatt, Ansu O., Tyner, Angela L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912439/
https://ncbi.nlm.nih.gov/pubmed/26983689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0450
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