INHIBITION OF HISTONE DEACETYLASE 6 ACTIVITY REDUCES CYST GROWTH IN POLYCYSTIC KIDNEY DISEASE

Abnormal proliferation of cyst-lining epithelium and increased intra-cystic fluid secretion via the cystic fibrosis transmembrane conductance regulator (CFTR) are thought to contribute to cyst growth in autosomal dominant polycystic kidney disease (ADPKD). Histone deacetylase 6 (HDAC6) expression an...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Kidney Int
Auteurs principaux: Cebotaru, Liudmila, Liu, Qiangni, Yanda, Murali, Boinot, Clement, Outeda, Patricia, Huso, David L., Watnick, Terry, Guggino, William B., Cebotaru, Valeriu
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912414/
https://ncbi.nlm.nih.gov/pubmed/27165822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.01.026
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires