Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury

Mutations in the complement regulatory proteins are associated with several different diseases. Although these mutations cause dysregulated alternative pathway activation throughout the body, the kidneys are the most common site of injury. The susceptibility of the kidney to alternative pathway medi...

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Veröffentlicht in:Kidney Int
Hauptverfasser: Laskowski, Jennifer, Renner, Brandon, Le Quintrec, Moglie, Panzer, Sarah, Hannan, Jonathan P., Ljubanovic, Danica, Ruseva, Marieta M., Borza, Dorin-Bogdan, Antonioli, Alexandra H., Pickering, Matthew C., Holers, V. Michael, Thurman, Joshua M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912413/
https://ncbi.nlm.nih.gov/pubmed/27165610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.02.036
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