Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion

Ischemia/reperfusion (I/R) of several organs results in complement activation, but the kidney is unique in that activation after I/R occurs only via the alternative pathway. We hypothesized that selective activation of this pathway after renal I/R could occur either because of a loss of complement i...

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Detalhes bibliográficos
Main Authors: Thurman, Joshua M., Ljubanović, Danica, Royer, Pamela A., Kraus, Damian M., Molina, Hector, Barry, Nicholas P., Proctor, Gregory, Levi, Moshe, Holers, V. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1352158/
https://ncbi.nlm.nih.gov/pubmed/16444293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24521
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