Aspirin Reduces Plasma Concentrations of the Oncometabolite 2-Hydroxyglutarate: Results of a Randomized, Double-Blind, Crossover Trial

BACKGROUND: Aspirin use is an effective strategy for the chemoprevention of colorectal cancer, even at low doses. However, in order to implement aspirin interventions, risk–benefit balances and biological mechanisms need to be better defined; to further this aim, we used a metabolomics approach. MET...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Epidemiol Biomarkers Prev
Auteurs principaux: Liesenfeld, David B., Botma, Akke, Habermann, Nina, Toth, Reka, Weigel, Christoph, Popanda, Odilia, Klika, Karel D., Potter, John D., Lampe, Johanna W., Ulrich, Cornelia M.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911817/
https://ncbi.nlm.nih.gov/pubmed/26585118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-15-0697
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