Chargement en cours...

HLA class I molecular variation and peptide-binding properties suggest a model of joint divergent asymmetric selection

The main function of HLA class I molecules is to present pathogen-derived peptides to cytotoxic T lymphocytes. This function is assumed to drive the maintenance of an extraordinary amount of polymorphism at each HLA locus, providing an immune advantage to heterozygote individuals capable to present...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Immunogenetics
Auteurs principaux: Buhler, Stéphane, Nunes, José Manuel, Sanchez-Mazas, Alicia
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911380/
https://ncbi.nlm.nih.gov/pubmed/27233953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-016-0918-x
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!