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HLA DNA Sequence Variation among Human Populations: Molecular Signatures of Demographic and Selective Events

Molecular differences between HLA alleles vary up to 57 nucleotides within the peptide binding coding region of human Major Histocompatibility Complex (MHC) genes, but it is still unclear whether this variation results from a stochastic process or from selective constraints related to functional dif...

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Detalhes bibliográficos
Main Authors: Buhler, Stéphane, Sanchez-Mazas, Alicia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051395/
https://ncbi.nlm.nih.gov/pubmed/21408106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014643
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