Systematic Identification of Anti-Fungal Drug Targets by a Metabolic Network Approach

New antimycotic drugs are challenging to find, as potential target proteins may have close human orthologs. We here focus on identifying metabolic targets that are critical for fungal growth and have minimal similarity to targets among human proteins. We compare and combine here: (I) direct metaboli...

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Dades bibliogràfiques
Publicat a:Front Mol Biosci
Autors principals: Kaltdorf, Martin, Srivastava, Mugdha, Gupta, Shishir K., Liang, Chunguang, Binder, Jasmin, Dietl, Anna-Maria, Meir, Zohar, Haas, Hubertus, Osherov, Nir, Krappmann, Sven, Dandekar, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2016
Matèries:
Molecular Biosciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911368/
https://ncbi.nlm.nih.gov/pubmed/27379244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2016.00022
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