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Arginine Auxotrophy Affects Siderophore Biosynthesis and Attenuates Virulence of Aspergillus fumigatus

Aspergillus fumigatus is an opportunistic human pathogen mainly infecting immunocompromised patients. The aim of this study was to characterize the role of arginine biosynthesis in virulence of A. fumigatus via genetic inactivation of two key arginine biosynthetic enzymes, the bifunctional acetylglu...

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Publicado en:Genes (Basel)
Autores principales: Dietl, Anna-Maria, Binder, Ulrike, Bauer, Ingo, Shadkchan, Yana, Osherov, Nir, Haas, Hubertus
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7231135/
https://ncbi.nlm.nih.gov/pubmed/32326414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11040423
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