mda-7/IL-24 induces cell death in neuroblastoma through a novel mechanism involving AIF and ATM

Advanced stages of neuroblastoma, the most common extracranial malignant solid tumor of the central nervous system in infants and children, are refractive to therapy. Ectopic expression of melanoma differentiation associated gene-7/Interleukin-24 (mda-7/IL-24) promotes broad-spectrum antitumor activ...

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Udgivet i:Cancer Res
Main Authors: Bhoopathi, Praveen, Lee, Nathaniel, Pradhan, Anjan K., Shen, Xue-Ning, Das, Swadesh K., Sarkar, Devanand, Emdad, Luni, Fisher, Paul B.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911293/
https://ncbi.nlm.nih.gov/pubmed/27197168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2959
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