mda-7/IL-24 induces cell death in neuroblastoma through a novel mechanism involving AIF and ATM

Advanced stages of neuroblastoma, the most common extracranial malignant solid tumor of the central nervous system in infants and children, are refractive to therapy. Ectopic expression of melanoma differentiation associated gene-7/Interleukin-24 (mda-7/IL-24) promotes broad-spectrum antitumor activ...

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Pubblicato in:Cancer Res
Autori principali: Bhoopathi, Praveen, Lee, Nathaniel, Pradhan, Anjan K., Shen, Xue-Ning, Das, Swadesh K., Sarkar, Devanand, Emdad, Luni, Fisher, Paul B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911293/
https://ncbi.nlm.nih.gov/pubmed/27197168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2959
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