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mda-7/IL-24 induces cell death in neuroblastoma through a novel mechanism involving AIF and ATM

Advanced stages of neuroblastoma, the most common extracranial malignant solid tumor of the central nervous system in infants and children, are refractive to therapy. Ectopic expression of melanoma differentiation associated gene-7/Interleukin-24 (mda-7/IL-24) promotes broad-spectrum antitumor activ...

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Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Bhoopathi, Praveen, Lee, Nathaniel, Pradhan, Anjan K., Shen, Xue-Ning, Das, Swadesh K., Sarkar, Devanand, Emdad, Luni, Fisher, Paul B.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911293/
https://ncbi.nlm.nih.gov/pubmed/27197168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2959
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