Pharmacokinetics of Rilpivirine in HIV-Infected Pregnant Women

BACKGROUND: Rilpivirine pharmacokinetics are defined by its absorption, distribution, metabolism, and excretion. Pregnancy can affect these factors by changes in cardiac output, protein binding, volume of distribution, and cytochrome P450 (CYP) 3A4 activity. Rilpivirine is metabolized by CYP3A4. The...

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Gepubliceerd in:J Acquir Immune Defic Syndr
Hoofdauteurs: Tran, Anna Hoang, Best, Brookie M., Stek, Alice, Wang, Jiajia, Capparelli, Edmund V., Burchett, Sandra K., Kreitchmann, Regis, Rungruengthanakit, Kittipong, George, Kathleen, Cressey, Tim R., Chakhtoura, Nahida, Smith, Elizabeth, Shapiro, David E., Mirochnick, Mark
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911231/
https://ncbi.nlm.nih.gov/pubmed/26918544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000968
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