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Pharmacokinetics of Rilpivirine in HIV-Infected Pregnant Women
BACKGROUND: Rilpivirine pharmacokinetics are defined by its absorption, distribution, metabolism, and excretion. Pregnancy can affect these factors by changes in cardiac output, protein binding, volume of distribution, and cytochrome P450 (CYP) 3A4 activity. Rilpivirine is metabolized by CYP3A4. The...
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| Vydáno v: | J Acquir Immune Defic Syndr |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4911231/ https://ncbi.nlm.nih.gov/pubmed/26918544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000968 |
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