Pharmacokinetics of Rilpivirine in HIV-Infected Pregnant Women

BACKGROUND: Rilpivirine pharmacokinetics are defined by its absorption, distribution, metabolism, and excretion. Pregnancy can affect these factors by changes in cardiac output, protein binding, volume of distribution, and cytochrome P450 (CYP) 3A4 activity. Rilpivirine is metabolized by CYP3A4. The...

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Vydáno v:J Acquir Immune Defic Syndr
Hlavní autoři: Tran, Anna Hoang, Best, Brookie M., Stek, Alice, Wang, Jiajia, Capparelli, Edmund V., Burchett, Sandra K., Kreitchmann, Regis, Rungruengthanakit, Kittipong, George, Kathleen, Cressey, Tim R., Chakhtoura, Nahida, Smith, Elizabeth, Shapiro, David E., Mirochnick, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911231/
https://ncbi.nlm.nih.gov/pubmed/26918544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000968
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