Darunavir pharmacokinetics with an increased dose during pregnancy

BACKGROUND: This study aims to evaluate the pharmacokinetics of an increased dose of darunavir (800 mg twice daily) with 100 mg ritonavir during pregnancy and postpartum. METHODS: Darunavir (DRV) and ritonavir (RTV; r) intensive pharmacokinetic evaluations were performed at steady state during the s...

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Pubblicato in:J Acquir Immune Defic Syndr
Autori principali: Eke, Ahizechukwu C., Stek, Alice M., Wang, Jiajia, Kreitchmann, Regis, Shapiro, David E., Smith, Elizabeth, Chakhtoura, Nahida, Capparelli, Edmund V., Mirochnick, Mark, Best, Brookie M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7258985/
https://ncbi.nlm.nih.gov/pubmed/31923087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000002261
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