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Pharmacokinetics of an Increased Atazanavir Dose with and without Tenofovir During the Third Trimester of Pregnancy

BACKGROUND: Reduced atazanavir exposure has been demonstrated during pregnancy with standard atazanavir/ritonavir dosing. We studied an increased dose during the third trimester of pregnancy. METHODS: IMPAACT 1026s is a prospective, non-blinded pharmacokinetic study of HIV-infected pregnant women ta...

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Detalhes bibliográficos
Main Authors: Kreitchmann, Regis, Best, Brookie M., Wang, Jiajia, Stek, Alice, Caparelli, Edmund, Watts, D. Heather, Smith, Elizabeth, Shapiro, David E., Rossi, Steve, Burchett, Sandra K., Hawkins, Elizabeth, Byroads, Mark, Cressey, Tim R., Mirochnick, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625451/
https://ncbi.nlm.nih.gov/pubmed/23392467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e318289b4d2
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