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Pharmacokinetics of an Increased Atazanavir Dose with and without Tenofovir During the Third Trimester of Pregnancy

BACKGROUND: Reduced atazanavir exposure has been demonstrated during pregnancy with standard atazanavir/ritonavir dosing. We studied an increased dose during the third trimester of pregnancy. METHODS: IMPAACT 1026s is a prospective, non-blinded pharmacokinetic study of HIV-infected pregnant women ta...

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Détails bibliographiques
Auteurs principaux: Kreitchmann, Regis, Best, Brookie M., Wang, Jiajia, Stek, Alice, Caparelli, Edmund, Watts, D. Heather, Smith, Elizabeth, Shapiro, David E., Rossi, Steve, Burchett, Sandra K., Hawkins, Elizabeth, Byroads, Mark, Cressey, Tim R., Mirochnick, Mark
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625451/
https://ncbi.nlm.nih.gov/pubmed/23392467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e318289b4d2
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