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Low-molecular-weight polymer–drug conjugates for synergistic anticancer activity of camptothecin and doxorubicin combinations
BACKGROUND: High-molecular-weight (MW) polymers (>50,000 Da) can be conjugated to chemotherapy drugs in order to improve their tumor accumulation, while low MW polymers ≤10,000 Da are often overlooked due to faster plasma clearance. Small polymers, however, may facilitate deeper tumor penetration...
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| Udgivet i: | Nanomedicine (Lond) |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Future Medicine Ltd
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4910946/ https://ncbi.nlm.nih.gov/pubmed/27079141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.16.33 |
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