Effects of the combination of camptothecin and doxorubicin or etoposide on rat glioma cells and camptothecin-resistant variants

From the rat C6 glioma cell line in culture, we selected camptothecin-resistant variants by growth in the presence of increasing amounts of this drug (C6(CPT10), C6(CPT50) and C6(CPT100), growing respectively with 10, 50 and 100 ng ml(–1)camptothecin). The degree of resistance to camptothecin ranged...

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Detalhes bibliográficos
Main Authors: Pavillard, V, Kherfellah, D, Richard, S, Robert, J, Montaudon, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2001
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375103/
https://ncbi.nlm.nih.gov/pubmed/11592782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2027
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