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A specific aptamer-cell penetrating peptides complex delivered siRNA efficiently and suppressed prostate tumor growth in vivo

Specific and efficient delivery of siRNA into intended tumor cells remains as a challenge, even though RNAi has been exploited as a new strategy for prostate cancer therapy. This work aims to address both specificity and efficiency of SURVIVIN-siRNA delivery by constructing a therapeutic complex usi...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Diao, Yanjun, Liu, Jiayun, Ma, Yueyun, Su, Mingquan, Zhang, Hongyi, Hao, Xiaoke
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910937/
https://ncbi.nlm.nih.gov/pubmed/26954374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1156266
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