Plasmid-based Stat3 siRNA delivered by hydroxyapatite nanoparticles suppresses mouse prostate tumour growth in vivo

DNA vector-based Stat3-specific RNA interference (si-Stat3) blocks Stat3 signalling and inhibits prostate tumour growth. However, the antitumour activity depends on the efficient delivery of si-Stat3. The effects on the growth of mouse prostate cancer cells of si-Stat3 delivered by hydroxyapatite we...

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Detalhes bibliográficos
Main Authors: Liang, Zuo-Wen, Guo, Bao-Feng, Li, Yang, Li, Xiao-Jie, Li, Xin, Zhao, Li-Jing, Gao, Li-Fang, Yu, Hao, Zhao, Xue-Jian, Zhang, Ling, Yang, Bao-Xue
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739337/
https://ncbi.nlm.nih.gov/pubmed/21297658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2010.167
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