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Oncogenic Ras modulates p38 MAPK-mediated inflammatory cytokine production in glioblastoma cells

Inflammation is an important factor promoting the progression of glioblastoma. In the present study we examined the contribution of Ras signaling and TNFα/IL-1β cytokines to the development of the glioblastoma inflammatory microenvironment. Enhanced activation of Ras through de-regulated activation...

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Publicat a:Cancer Biol Ther
Autors principals: Munoz, Lenka, Yeung, Yiu To, Grewal, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910925/
https://ncbi.nlm.nih.gov/pubmed/26794430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1139249
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