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Melanoma driver mutations and immune therapy

Melanoma harbors recurrent oncogenic driver mutations in BRAF and NRAS, but these mutations' impact on immunotherapy outcomes is unclear. We assessed 229 patients treated with immunotherapy, and found that clinical outcomes were largely superior in those with NRAS mutations. Herein, we discuss...

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Publicado en:Oncoimmunology
Autores principales: Johnson, Douglas B., Lovly, Christine M., Sullivan, Ryan J., Carvajal, Richard D., Sosman, Jeffrey A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910708/
https://ncbi.nlm.nih.gov/pubmed/27467925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1051299
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