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Melanoma driver mutations and immune therapy

Melanoma harbors recurrent oncogenic driver mutations in BRAF and NRAS, but these mutations' impact on immunotherapy outcomes is unclear. We assessed 229 patients treated with immunotherapy, and found that clinical outcomes were largely superior in those with NRAS mutations. Herein, we discuss...

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Podrobná bibliografie
Vydáno v:Oncoimmunology
Hlavní autoři: Johnson, Douglas B., Lovly, Christine M., Sullivan, Ryan J., Carvajal, Richard D., Sosman, Jeffrey A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910708/
https://ncbi.nlm.nih.gov/pubmed/27467925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1051299
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