P53 Is Involved in a Three-Dimensional Architecture-Mediated Decrease in Chemosensitivity in Colon Cancer

Three-dimensional (3D) culture models represent a better approximation of solid tumor tissue architecture, especially cell adhesion, in vivo than two-dimensional (2D) cultures do. Here, we explored the role of architecture in chemosensitivity to platinum in colon cancer. Under the 3D culture conditi...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: He, Jianming, Liang, Xi, Luo, Fen, Chen, Xuedan, Xu, Xueqing, Wang, Fengchao, Zhang, Zhenping
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910581/
https://ncbi.nlm.nih.gov/pubmed/27313779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.14506
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