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Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) exhibits specific tumoricidal activity and is under development for cancer therapy. Mismatch-repair-deficient colonic tumors evade TRAIL-induced apoptosis through mutational inactivation of Bax, but chemotherapeutics including Camptosar...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC299914/ https://ncbi.nlm.nih.gov/pubmed/14645705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2435285100 |
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