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Small-molecule modulators of p53 family signaling and antitumor effects in p53-deficient human colon tumor xenografts
p53 deficiency is common in almost all human tumors and contributes to an aggressive chemo- or radiotherapy-resistant phenotype, therefore providing a target for drug development. Molecular targeting to restore wild-type p53 activity has been attempted in drug development and has led to the identifi...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2006
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1544164/ https://ncbi.nlm.nih.gov/pubmed/16835297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604507103 |
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