BRCA1 and BRCA2 rearrangements in Brazilian individuals with Hereditary Breast and Ovarian Cancer Syndrome

Approximately 5-10% of breast cancers are caused by germline mutations in high penetrance predisposition genes. Among these, BRCA1 and BRCA2, which are associated with the Hereditary Breast and Ovarian Cancer (HBOC) syndrome, are the most frequently affected genes. Recent studies confirm that gene r...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genet Mol Biol
Main Authors: Ewald, Ingrid Petroni, Cossio, Silvia Liliana, Palmero, Edenir Inez, Pinheiro, Manuela, Nascimento, Ivana Lucia de Oliveira, Machado, Taisa Manuela Bonfim, Sandes, Kiyoko Abe, Toralles, Betânia, Garicochea, Bernardo, Izetti, Patricia, Pereira, Maria Luiza Saraiva, Bock, Hugo, Vargas, Fernando Regla, Moreira, Miguel Ângelo Martins, Peixoto, Ana, Teixeira, Manuel R., Ashton-Prolla, Patricia
Format: Artigo
Jezik:Inglês
Izdano: Sociedade Brasileira de Genética 2016
Teme:
Special Oncogenetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910561/
https://ncbi.nlm.nih.gov/pubmed/27303907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1678-4685-GMB-2014-0350
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