Screening for germline BRCA1, BRCA2, TP53 and CHEK2 mutations in families at-risk for hereditary breast cancer identified in a population-based study from Southern Brazil

In Brazil, breast cancer is a public health care problem due to its high incidence and mortality rates. In this study, we investigated the prevalence of hereditary breast cancer syndromes (HBCS) in a population-based cohort in Brazils southernmost capital, Porto Alegre. All participants answered a q...

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Detalhes bibliográficos
Publicado no:Genet Mol Biol
Main Authors: Palmero, Edenir Inêz, Alemar, Bárbara, Schüler-Faccini, Lavínia, Hainaut, Pierre, Moreira-Filho, Carlos Alberto, Ewald, Ingrid Petroni, dos Santos, Patricia Koehler, Ribeiro, Patricia Lisbôa Izetti, de Oliveira, Cristina Brinkmann, Kelm, Florence Le Calvez, Tavtigian, Sean, Cossio, Silvia Liliana, Giugliani, Roberto, Caleffi, Maira, Ashton-Prolla, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: Sociedade Brasileira de Genética 2016
Assuntos:
Special Oncogenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910552/
https://ncbi.nlm.nih.gov/pubmed/27223485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1678-4685-GMB-2014-0363
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