Genomic rearrangements in BRCA1 and BRCA2: A literature review

Women with mutations in the breast cancer genes BRCA1 or BRCA2 have an increased lifetime risk of developing breast, ovarian and other BRCA-associated cancers. However, the number of detected germline mutations in families with hereditary breast and ovarian cancer (HBOC) syndrome is lower than expec...

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Detalhes bibliográficos
Main Authors: Ewald, Ingrid Petroni, Ribeiro, Patricia Lisboa Izetti, Palmero, Edenir Inêz, Cossio, Silvia Liliana, Giugliani, Roberto, Ashton-Prolla, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: Sociedade Brasileira de Genética 2009
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036053/
https://ncbi.nlm.nih.gov/pubmed/21637503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1415-47572009005000049
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