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Comparison of multiple genotyping methods for the identification of the cancer predisposing founder mutation p.R337H inTP53
Germline mutations in the TP53 gene are associated with Li-Fraumeni and Li-Fraumeni-Like Syndromes, characterized by increased predisposition to early-onset cancers. In Brazil, the prevalence of the TP53-p.R337H germline mutation is exceedingly high in the general population and in cancer-affected p...
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| Publicado no: | Genet Mol Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Sociedade Brasileira de Genética
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4910550/ https://ncbi.nlm.nih.gov/pubmed/27275664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1678-4685-GMB-2014-0351 |
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