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IgE-mediated enhancement of CD4(+) T cell responses requires antigen presentation by CD8α(−) conventional dendritic cells

IgE, forming an immune complex with small proteins, can enhance the specific antibody and CD4(+) T cell responses in vivo. The effects require the presence of CD23 (Fcε-receptor II)(+) B cells, which capture IgE-complexed antigens (Ag) in the circulation and transport them to splenic B cell follicle...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ding, Zhoujie, Dahlin, Joakim S., Xu, Hui, Heyman, Birgitta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910288/
https://ncbi.nlm.nih.gov/pubmed/27306570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28290
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