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IgG3-antigen complexes are deposited on follicular dendritic cells in the presence of C1q and C3

IgG3, passively administered together with small proteins, induces enhanced primary humoral responses against these proteins. We previously found that, within 2 h of immunization, marginal zone (MZ) B cells capture IgG3-antigen complexes and transport them into splenic follicles and that this requir...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Zhang, Lu, Ding, Zhoujie, Heyman, Birgitta
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511153/
https://ncbi.nlm.nih.gov/pubmed/28710441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05704-3
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