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IgG3-antigen complexes are deposited on follicular dendritic cells in the presence of C1q and C3

IgG3, passively administered together with small proteins, induces enhanced primary humoral responses against these proteins. We previously found that, within 2 h of immunization, marginal zone (MZ) B cells capture IgG3-antigen complexes and transport them into splenic follicles and that this requir...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Lu, Ding, Zhoujie, Heyman, Birgitta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511153/
https://ncbi.nlm.nih.gov/pubmed/28710441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05704-3
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