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Visualizing the formation of an RNA folding intermediate through a fast highly modular secondary structure switch
Intermediates play important roles in RNA folding but can be difficult to characterize when short-lived or not significantly populated. By combining (15)N relaxation dispersion NMR with chemical probing, we visualized a fast (k(ex)=k(1)+k(−1)≈423 s(−1)) secondary structural switch directed towards a...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4909931/ https://ncbi.nlm.nih.gov/pubmed/27292179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11768 |
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