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BMP2, a key to uncover luminal breast cancer origin linked to pollutant effects on epithelial stem cells niche
Chronic exposure of epithelial cells to high levels of bone morphogenetic protein 2 (BMP2) has recently been demonstrated to initiate stem cell transformation toward a luminal tumor-like phenotype through a BMP2–BMPR1B-dependent mechanism. Carcinogen-driven deregulation of the stem cell niche could...
Gespeichert in:
| Veröffentlicht in: | Mol Cell Oncol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4909443/ https://ncbi.nlm.nih.gov/pubmed/27314065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1026527 |
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