Disequilibrium of BMP2 Levels in the Breast Stem Cell Niche Launches Epithelial Transformation by Overamplifying BMPR1B Cell Response

Understanding the mechanisms of cancer initiation will help to prevent and manage the disease. At present, the role of the breast microenvironment in transformation remains unknown. As BMP2 and BMP4 are important regulators of stem cells and their niches in many tissues, we investigated their functi...

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Gepubliceerd in:Stem Cell Reports
Hoofdauteurs: Chapellier, Marion, Bachelard-Cascales, Elodie, Schmidt, Xenia, Clément, Flora, Treilleux, Isabelle, Delay, Emmanuel, Jammot, Alexandre, Ménétrier-Caux, Christine, Pochon, Gaëtan, Besançon, Roger, Voeltzel, Thibault, Caron de Fromentel, Claude, Caux, Christophe, Blay, Jean-Yves, Iggo, Richard, Maguer-Satta, Véronique
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325271/
https://ncbi.nlm.nih.gov/pubmed/25601208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.12.007
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