PDK1 is a Regulator of Epidermal Differentiation that Activates and Organizes Asymmetric Cell Division

Asymmetric cell division (ACD) in a perpendicular orientation promotes cell differentiation and organizes the stratified epithelium. However, the upstream cues regulating ACD have not been identified. Here we report that phosphoinositide-dependent kinase 1 (PDK1) plays a critical role in establishin...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Dainichi, Teruki, Hayden, Matthew S., Park, Sung-Gyoo, Oh, Hyunju, Seeley, John J., Grinberg-Bleyer, Yenkel, Beck, Kristen M., Miyachi, Yoshiki, Kabashima, Kenji, Hashimoto, Takashi, Ghosh, Sankar
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909264/
https://ncbi.nlm.nih.gov/pubmed/27184845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.051
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