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Hormonal Responses to Cholinergic Input Are Different in Humans with and without Type 2 Diabetes Mellitus

Peripheral muscarinic acetylcholine receptors regulate insulin and glucagon release in rodents but their importance for similar roles in humans is unclear. Bethanechol, an acetylcholine analogue that does not cross the blood-brain barrier, was used to examine the role of peripheral muscarinic signal...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chowdhury, Sara, Wang, Songyan, Dunai, Judit, Kilpatrick, Rachel, Oestricker, Lauren Z., Wallendorf, Michael J., Patterson, Bruce W., Reeds, Dominic N., Wice, Burton M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909255/
https://ncbi.nlm.nih.gov/pubmed/27304975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156852
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