Acute heart failure with cardiomyocyte atrophy induced in adult mice by ablation of cardiac myosin light chain kinase

AIMS: Under pressure overload, initial adaptive hypertrophy of the heart is followed by cardiomyocyte elongation, reduced contractile force, and failure. The mechanisms governing the transition to failure are not fully understood. Pressure overload reduced cardiac myosin light chain kinase (cMLCK) b...

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Veröffentlicht in:Cardiovasc Res
Hauptverfasser: Massengill, Michael T., Ashraf, Hassan M., Chowdhury, Rajib R., Chrzanowski, Stephen M., Kar, Jeena, Warren, Sonisha A., Walter, Glenn A., Zeng, Huadong, Kang, Byung-Ho, Anderson, Robert H., Moss, Richard L., Kasahara, Hideko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909160/
https://ncbi.nlm.nih.gov/pubmed/27025239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvw069
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