Acute heart failure with cardiomyocyte atrophy induced in adult mice by ablation of cardiac myosin light chain kinase

AIMS: Under pressure overload, initial adaptive hypertrophy of the heart is followed by cardiomyocyte elongation, reduced contractile force, and failure. The mechanisms governing the transition to failure are not fully understood. Pressure overload reduced cardiac myosin light chain kinase (cMLCK) b...

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Détails bibliographiques
Publié dans:Cardiovasc Res
Auteurs principaux: Massengill, Michael T., Ashraf, Hassan M., Chowdhury, Rajib R., Chrzanowski, Stephen M., Kar, Jeena, Warren, Sonisha A., Walter, Glenn A., Zeng, Huadong, Kang, Byung-Ho, Anderson, Robert H., Moss, Richard L., Kasahara, Hideko
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909160/
https://ncbi.nlm.nih.gov/pubmed/27025239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvw069
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