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Ablation of Nkx2-5 at mid-embryonic stage results in premature lethality and cardiac malformation
AIMS: Human congenital heart disease linked to mutations in the homeobox transcription factor, NKX2-5, is characterized by cardiac anomalies, including atrial and ventricular septal defects as well as conduction and occasional defects in contractility. In the mouse, homozygous germline deletion of N...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3125071/ https://ncbi.nlm.nih.gov/pubmed/21285290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvr037 |
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