Ablation of Nkx2-5 at mid-embryonic stage results in premature lethality and cardiac malformation

AIMS: Human congenital heart disease linked to mutations in the homeobox transcription factor, NKX2-5, is characterized by cardiac anomalies, including atrial and ventricular septal defects as well as conduction and occasional defects in contractility. In the mouse, homozygous germline deletion of N...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Terada, Ryota, Warren, Sonisha, Lu, Jonathan T., Chien, Kenneth R., Wessels, Andy, Kasahara, Hideko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2011
Gaiak:
Original Article: Spotlight on Cardiac Development
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125071/
https://ncbi.nlm.nih.gov/pubmed/21285290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvr037
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