PGC1α-dependent NAD biosynthesis links oxidative metabolism to renal protection

The energetic burden of continuously concentrating solutes against gradients along the tubule may render the kidney especially vulnerable to ischemia. Indeed, acute kidney injury (AKI) affects 3% of all hospitalized patients.(1,2) Here we show that the mitochondrial biogenesis regulator, PGC1α,(3,4)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nature
Egile Nagusiak: Tran, Mei T., Zsengeller, Zsuzsanna K., Berg, Anders H., Khankin, Eliyahu V., Bhasin, Manoj K., Kim, Wondong, Clish, Clary B., Stillman, Isaac E., Karumanchi, S. Ananth, Rhee, Eugene P., Parikh, Samir M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909121/
https://ncbi.nlm.nih.gov/pubmed/26982719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17184
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak